William Dupuy was born in 1809 in Greenup County, Kentucky. He appeared on the census in 1840 in Greenup County, Kentucky. He appeared on the census on 12 Aug 1850 in Greenup County, Kentucky. He appeared on the census on 7 Aug 1860 in P. O. Pleasant Hill, Division 35, Jackson County, Missouri. He appeared on the census on 14 Jun 1870 in P. O. Lee Summit, Jackson County, Missouri. He appeared on the census on 1 Jun 1880 in Prairie Township, Jackson County, Missouri. He died before 1900 in Missouri.

He was married to Anne Littlejohn on 13 May 1835 in Greenup County, Kentucky. Anne Littlejohn was born in 1809 in Kentucky. She died before 1870 in Missouri. William Dupuy and Anne Littlejohn had the following children:

Richard Dupuy was born in 1836 in Greenup County, Kentucky.
Mary A. Dupuy.

He was married to Anna Heart on 18 Nov 1877 in Jackson County, Missouri. Anna Heart was born in May 1838 in Kentucky. She appeared on the census on 23 Jun 1900 in Foster, Walnut Township, Bates County, Missouri. (201)1094

Sources:
1840 US Federal Census. Greenup County, Kentucky, 100011-101001-0.
1850 US Federal Census. Greenup County, Kentucky, p. 239, No. 301/305, age 41, farmer, $3000, b. KY.
1860 US Federal Census. P. O. Pleasant Hill, Division 35, Jackson County, Missouri, p. 213, No. 1632/1714, age 57, farmer, $5,000/400, b. KY.
1870 US Federal Census. P. O. Lee Summit, Jackson County, Missouri, p. 87, No. 219/237,
age 63, farmer, $14,000/11,000, b. KY, with daughter Mary.
1880 US Federal Census. Prairie Township, Jackson County, Missouri, ED 35, sh 1, No. 6/6,
age 70, b. KY,VA,VA, farmer, with wife Anne, age 40, b. KY,KY,KY.
1900 US Federal Census. Foster, Walnut Township, Bates County, Missouri, ED 24, sh 13a, p. 320a, No. 231/237, b. May 1838, KY,KY,KY, no children, living with sister Mary.